Yes people do switch job/ change during, after the quarantine: They find working from home, virtually enjoyable and allow them the flexibility AND even employers like the cost saving of people working virtually so it's a win-win in some situation.
As for jobs in general, there's tons of opening right now and sure a college degree may not be essential but the skills are. I know a person who didn't go to college but learn the skill self taught and got hired over college grads. So yes, there are ways but essential to have the skills.