Cromartie was wacky. It was funny but it wasn't something I could sit and watch in one sitting. Just too far out there but the characters were macabre.
Gunbuster (uncut) is a classic. Reminds me a lot like Ender's Game. Do not get the US release. They hacked it and the spin off Killbuster (or something) was disappointing.
My choice is
The Tatami Galaxy
It's about a college grad looking for love but can't find it, even when it's dangling right before him. Artwork is different, characters are memorable and each episode is well written in scope of the entire series. Lastly if you really want to practice your Japanese then this series will test your reading, hearing and comprehension skills. Crack speed dialogue.
Some other notable entries are Bubblegum Crisis (strong female roles in hardsuits) and Gunsmith Cats (women into guns, bombs, cars and they're bounty hunters) along with Riding Bean.